- #Comprehensive meta analysis version 2 crack software
- #Comprehensive meta analysis version 2 crack crack
Several researchers have found that in high myopic eyes, the choroidal thickness is significantly thinner than in normal eyes. With the enhanced depth imaging (EDI) technique of optical coherence tomography (OCT) instruments, images of the choroid have improved, making it possible to measure choroidal thickness more accurately, safely, and simply.
Choroidal thickness may be an important parameter in studying the pathogenesis of high myopia. Īs we all know, in high myopic eyes, the earliest changes begin in the choroid recent interest has focused on the choroid as an important structure involved in the pathophysiology of high myopia. Myopic CNV develops into secondary chorioretinal central atrophy and leads to central scotoma. Another notable complication threatening visual function is CNV. Among these complications, chorioretinal atrophy, augmented by choroidal thinning, can lead to photoreceptor cell death, which results in the consequent loss of central visual function. Excessive axial elongation of the eyeball is thought to be one of the main causes of the ocular complications mentioned above.
#Comprehensive meta analysis version 2 crack crack
High myopia is always accompanied by pathological structural changes, such as axial elongation, posterior scleral staphyloma, lacquer crack formation, thinning of the retina and chorioid, and choroidal neovascularization (CNV). It has been reported that about 1 % of the population suffers from this disease. High myopia is one of the main causes of visual impairment worldwide. The presence of CNV and of lacquer cracks is associated strongly with eyes with thinner macular choroids. This might be secondary to the longer AL but it is not an independent factor.
The present study, along with the comprehensive meta-analysis, indicated that in the Chinese population, the choroidal thickness in high myopic eyes was thinner than that of normal control eyes, even across different subgroups. The result of our cross-sectional study is consistent with the results of the further meta-analysis with the pooled weighted mean difference (WMD) of −116.30 μm (95 % CI: −145.68, −86.92) for SFCT. Subgroup analysis showed that the high myopia with CNV and with lacquer cracks had a significantly thinner choroid than without CNV or lacquer crack eyes.
Multivariable linear regression analysis showed that the subfoveal choroidal thickness (SFCT) was not significantly thinner in association with the diagnosis. The high myopic eyes had a thinner choroid than the control eyes at all macular locations (all P < 0.001).
#Comprehensive meta analysis version 2 crack software
The meta-analyses were conducted using the Stata software package. In the high myopic eyes, subgroup analysis of macular choroidal thickness was performed in eyes with or without lacquer cracks and choroidal neovascularization (CNV). Univariate and multivariate linear regression analyses were performed to assess the association between choroidal thickness and clinical factors such as axial length (AL), spherical equivalent (SE), and central corneal thickness. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the macular choroidal thickness of high myopic eyes and normal control eyes were measured and compared at each location. We first conducted a cross-sectional study and then performed a meta-analysis to address this issue further. The purpose of this study was to examine the choroidal thickness of patients with high myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare them with healthy subjects.